HORDB

ID: hor003377
Uniprot ID: A0A158TFP8
Protein name: Orcokinin
Gene name: ORCK
Organism: Cancer borealis (Jonah crab)
Family: Orcokinin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Cancer (genus), Cancridae (family), Cancroidea (superfamily), Heterotremata, Eubrachyura, Brachyura (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction
GO CC: NA

Sequence: NFDEIDRSGFGF
Length: 12
Propeptide: MTRDVICTALLLALCVMASEGAIKDTPTHPANQPDAGYPADGSAAKRFDAFTTGFGHSKRNFDEIDRSGFGFAKRNFDEIDRSGFGFAKRNFDEIDRSGFGFAKRNFDEIDRSGFGFAKRNFDEIDRSSFGFNKRNFDEIDRSSFGFVKRMLTPRDLANLYKRNFDEIDRSGFGFVRRNAE
Signal peptide: MTRDVICTALLLALCVMASEG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor003377_AF2.pdb

hor003377_ESM.pdb

Mass:	159985	Formula:	C63H86N16O21
Absent amino acids:	ACHKLMPQTVWY	Common amino acids:	F
pI:	3.88	Basic residues:	1
Polar residues:	4	Hydrophobic residues:	4
Hydrophobicity:	-60	Boman Index:	-3347
Half-Life:	1.4 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	32.5
Instability Index:	5330.83	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 18700782
Title: Combining Microdialysis, NanoLC-MS, and MALDI-TOF/TOF to Detect Neuropeptides Secreted in the Crab, Cancer Borealis